2016 Mercedes-Benz S-Class
Fuel economy, running costs, emissions and safety · from U.S. EPA and NHTSA data
The 2016 Mercedes-Benz S-Class is sold in the U.S. with gasoline and plug-in hybrid power. The EPA lists 9 configurations for this model year, with combined economy from 15 to 26 MPG and an estimated annual fuel cost of $3,050 to $5,300 at 15,000 miles.
Key numbers
| Model year | 2016 |
|---|---|
| Vehicle class | Large Cars |
| Fuel type(s) | Gasoline, Plug-in Hybrid |
| Combined economy | 15-26 MPG |
| Best / worst combined | 26 / 15 MPG |
| Annual fuel cost | $3,050-$5,300 |
| Tailpipe CO₂ | 227-585 g/mi |
| EPA smog rating | 6-9 / 10 |
What it costs to fuel
Across its configurations, the 2016 S-Class costs about $3,050 to $5,300 a year to fuel at the EPA's 15,000-mile basis, averaging roughly $4,439. Over five years that is about $22,194 in fuel alone before maintenance, insurance and depreciation — which is why the running cost, not just the price, decides what a car really costs.
Relative to an average new vehicle, this S-Class configuration spends about $750 more on fuel over five years.
For context, the average combined economy of large cars in this dataset is about 29 MPG. The S-Class sits roughly 9 MPG below that mark at its midpoint, making it thirstier than average for its EPA class.
Configurations and fuel economy
| Version | Engine | Drive | Trans | Fuel | Combined | Annual fuel |
|---|---|---|---|---|---|---|
| S550e | 3.0L 6-cyl turbo | Rear-Wheel | Automatic | Plug-in Hybrid | 26 MPG | $3,050 |
| S550 | 4.7L 8-cyl turbo | Rear-Wheel | Automatic | Gasoline | 20 MPG | $4,000 |
| S550 4matic Coupe | 4.7L 8-cyl turbo | 4-Wheel | Automatic | Gasoline | 19 MPG | $4,200 |
| S550 4matic | 4.7L 8-cyl turbo | 4-Wheel | Automatic | Gasoline | 19 MPG | $4,200 |
| AMG S63 4matic | 5.5L 8-cyl turbo | 4-Wheel | Automatic | Gasoline | 18 MPG | $4,450 |
| AMG S63 4matic Coupe | 5.5L 8-cyl turbo | 4-Wheel | Automatic | Gasoline | 18 MPG | $4,450 |
| S600 | 6.0L 12-cyl turbo | Rear-Wheel | Automatic | Gasoline | 16 MPG | $5,000 |
| AMG S65 Coupe | 6.0L 12-cyl turbo | Rear-Wheel | Automatic | Gasoline | 15 MPG | $5,300 |
| AMG S65 | 6.0L 12-cyl turbo | Rear-Wheel | Automatic | Gasoline | 15 MPG | $5,300 |
Emissions, safety and size
The 2016 S-Class records tailpipe CO₂ of 227-585 g/mi, an EPA smog rating of 6-9 out of 10, and an EPA electric range of 450 to 450 miles when running on battery. The EPA classifies it as large cars.
Compare this car
Open the comparison tool to line this 2016 S-Class up against any other vehicle in the database, or jump to other years and trims from the 2016 Mercedes-Benz S-Class overview.
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Data: U.S. EPA FuelEconomy.gov (public domain) and NHTSA SafetyRatings. Figures are EPA estimates; real-world results vary.